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Figure 5 | BMC Pharmacology and Toxicology

Figure 5

From: Population pharmacokinetic and pharmacodynamic modeling of transformed binary effect data of triflusal in healthy Korean male volunteers: a randomized, open-label, multiple dose, crossover study

Figure 5

Results of model evaluation. (a) Visual predictive check result. The 5th and 95th percentiles (dashed gray line) and the median value (solid black line) from the simulated data are plotted against the observed concentration data (circle) according to time. (b) Predicted HTB concentration-probability of IPA curve; Circle: expected IPA for each HTB concentration measured at the time of PD observation; IPA, inhibition of platelet aggregation.

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BMC Pharmacology and Toxicology

ISSN: 2050-6511

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