Skip to main content

Table 1 Symbolic notations used and corresponding units

From: Modeling of chemical inhibition from amyloid protein aggregation kinetics

Insulin aggregation kinetics measured by absorbance or fluorescence  
X : Amyloid aggregation growth measured as absorbance at 600 nm, relative ThT fluorescence intensity (%) and ThT fluorescence intensity at 482 nm or 490 nm. Units: absorbance units (AU) or (%).
t : Time. Units: h or d
X m : Maximum aggregation growth. Units: AU or %
v m : Maximum aggregation rate. Units: AU h−1, AU d−1 or % h−1
λ : Lag phase. Units: h or d
X m : Maximum insulin aggregation affected by chemical agent. Units: AU or %
v m : Maximum insulin aggregation rate affected by chemical agent. Units: AU h−1, AU d−1 or % h−1
λ• : Lag phase affected by chemical agent. Units: h or d
Concentration effects on insulin aggregation kinetics  
C : Concentration of chemical agent. Units: mM or μM
K x : Maximum response affecting on X m . Dimensionless
m x : Concentration corresponding to the semi-maximum response affecting on X m . Units: mM or μM
a x : Shape parameter affecting on X m . Dimensionless
K v : Maximum response affecting on v m . Dimensionless
m v : Concentration corresponding to the semi-maximum response affecting on v m . Units: mM or μM
a v : Shape parameter affecting on v m . Dimensionless
K λ : Maximum response affecting on λ. Dimensionless
m λ : Concentration corresponding to the semi-maximum response affecting on λ. Units: mM or μM
a λ : Shape parameter affecting on λ. Dimensionless