Author, year | Treatment (dose, time of treatment) | ||
---|---|---|---|
Hesketh [18] | |||
Dolasetron (1.2 mg/kg, BC) | Dolasetron (1.8 mg/kg, BC) | Dolasetron (2.4 mg/kg, BC) | |
QT prolongation* | 11 ms | 27 ms | 39 ms |
PR prolongation† | 1 ms | 10 ms | 22 ms |
Gralla [19] | |||
Palonosetron (0.25 mg, BC) | Palonosetron (0.75 mg, BC) | Ondansetron (32 mg, BC) | |
QT prolongation* | 1 ms | 2 ms | 5 ms |
PR prolongation | NS | NS | NS |
Kim [20] | |||
Dolasetron (100, BC+ 800 mg, AC) | Ondansetron (8 mg, BC + 80 mg, AC) | ||
QT prolongation | NS | NS | |
PR prolongation | NS | NS |