From: Differentiation between first and second messenger effects of cGMP
Model
extracellular cGMP effect
Ref.
rat model of colorectal pain
analgesic (oral cGMP)
[7]
oxidative glutamate toxicity in HT22 cells
neuroprotective
[8]
kainate receptor-mediated neurotransmitter release
inhibition
[9]
glycine receptor-induced chloride current
accelerates desensitization
[10]