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Figure 2 | BMC Pharmacology and Toxicology

Figure 2

From: CYP2B6*6, CYP2B6*18, Body weight and sex are predictors of efavirenz pharmacokinetics and treatment response: population pharmacokinetic modeling in an HIV/AIDS and TB cohort in Zimbabwe

Figure 2

Basic goodness of fit plots for the final EFV PK model. The observations are plotted versus the population predictions. Upper right panel: The observations are plotted against the individual predictions. Lower left panel: The individually weighted residuals are plotted versus time after dose. Lower right panel: The absolute values of the individually weighted residuals are seen versus the individual predictions. The predictions match the observations and the residuals are distributed evenly around the reference line over time and do not give a pronounced slope over the predicted concentration range.

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