Table 2 Association between log transformed EFV concentration and categorical explanatory variables.
Variable | Mean Log EFV concentration | p-value | CV |
|---|---|---|---|
Gender | 0.195 | 74% | |
Male | 1.68 | ||
Female | 1.46 | ||
CYP 2B6*6 | 0.008* | 68% | |
GG | 1.16 | ||
GT | 1.55 | ||
TT | 2.35 | ||
CYP 2B6*18 | <0.001*** | 69% | |
TT | 1.35 | ||
TC | 2.22 | ||
CC | 3.01 | ||
ABCB1 1236C/T | 0.841 | 74% | |
CC | 1.60 | ||
CT | 1.56 | ||
TT | 1.30 | ||
CYP 2A6*9 | 0.004** | 72% | |
GG | 1.47 | ||
AA | 2.21 | ||
CYP 2A6*17 | 0.694 | 74% | |
AA | 1.92 | ||
AG | 1.45 | ||
GG | 1.62 | ||
CNS Toxicity | 0.122 | 73% | |
Yes | 1.72 | ||
No | 1.43 | ||
Regimen | 0.619 | 73% | |
TDF/3TC/EFV | 1.434 | ||
AZT/3TC/EFV | 1.510 | ||
D4T/3TC/EFV | 1.655 | ||
ART Only | 1.452 | 0.334 | 79% |
ART + anti-TB Therapy | 1.618 |