Table 4 Summary of statistical analysis of proton pump inhibitor comparison (Study 2)
Danirixin 100 mg Fasted + PPI | Danirixin 100 mg Fasted | Treatment Difference (Fasted + PPI vs. Fasted) | ||||
|---|---|---|---|---|---|---|
n | Adjusted Geometric Mean (SE Logs) | n | Adjusted Geometric Mean (SE Logs) | Estimate | 90 % CI | |
AUC (0-∞)(ng h/mL) | 12 | 6220 (0.1705) | 13 | 14,020 (0.1659) | 0.444 | (0.337, 0.584) |
Cmax(ng/mL) | 15 | 813 (0.1646) | 15 | 2235 (0.1646) | 0.364 | (0.267, 0.496) |