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Table 4 Summary of statistical analysis of proton pump inhibitor comparison (Study 2)

From: The pharmacokinetics and pharmacodynamics of danirixin (GSK1325756) − a selective CXCR2 antagonist − in healthy adult subjects

  Danirixin 100 mg Fasted + PPI Danirixin 100 mg Fasted Treatment Difference (Fasted + PPI vs. Fasted)
  n Adjusted Geometric Mean (SE Logs) n Adjusted Geometric Mean (SE Logs) Estimate 90 % CI
AUC (0-∞)(ng h/mL) 12 6220 (0.1705) 13 14,020 (0.1659) 0.444 (0.337, 0.584)
Cmax(ng/mL) 15 813 (0.1646) 15 2235 (0.1646) 0.364 (0.267, 0.496)