Table 3 Composition of induced sputum (pre- vs. post-baseline ozone, n = 24)

Viability

%

85.2 (9.4)

89.3 (11.3)

TCC

10⁶/mL

1.5 (0.9)

3.8 (3.6)***

WBC

10⁶/mL

1.5 (1.0)

3.7 (3.8)***

Macrophages

% nSq

70.2 (22.6)

25.2 (21.9)***

% WBC

72.2 (28.0)

25.5 (23.7)***

cells/g

1.0 (0.6)

0.7 (1.0)

CD14+ Monocytes

% nSq

1.9 (1.9)

5.7 (2.4)***

% WBC

1.9 (2.0)

5.7 (2.1)***

cells/g

0.0 (0.1)

0.2 (0.2)***

Neutrophils

% nSq

23.6 (21.6)

64.5 (27.3)***

% WBC

24.4 (23.5)

67.0 (24.8)***

cells/g

0.2 (0.6)

2.2 (2.4)***

Lymphocytes

% nSq

1.5 (1.6)

0.6 (1.2)*

%WBC

1.7 (1.5)

0.6 (1.2)*

cells/g

0.0 (0.0)

0.0 (0.1)

Eosinophils

% nSq

0.0 (0.5)

0.3 (0.5)

% WBC

0.0 (0.5)

0.3 (0.6)

cells/g

0.0 (0.0)

0.0 (0.0)

Epithelial cells

% nSq

1.4 (4.9)

1.2 (1.4)

cells/g

0.0 (0.1)

0.0 (0.0)

Squamous cells

%

13.5 (16.2)

3.8 (8.2)

IL8

pg/ml

639.6 (496.5)

1101.8 (723.1)***

IL6

pg/ml

13.1 (9.1)

39.9 (49.4)***

IL1B

pg/ml

22.8 (20.3)

36.2 (40.5)***

MMP9

ng/ml

50.9 (71.6)

152.6 (168.5)***