TY - JOUR AU - Panitz, Daniel AU - Swamy, Harsha AU - Nehrke, Keith PY - 2015 DA - 2015/12/04 TI - A C. elegans model of electronic cigarette use: Physiological effects of e-liquids in nematodes JO - BMC Pharmacology and Toxicology SP - 32 VL - 16 IS - 1 AB - Electronic cigarettes (e-cigs) have recently become very popular particularly among the younger generation. These nicotine delivery devices are viewed as a preferable alternative to more conventional forms of tobacco use and are thought to reduce the risk of chronic obstructive pulmonary disease, the third leading cause of death worldwide. However, there is very little data available on the consequences of e-cig use, though recently nicotine-independent inflammatory responses have been reported. The genetic model organism Caenorhabditis elegans is a soil nematode whose cell biology is remarkably well conserved with mammals. Here, we used C. elegans to test the physiologic effects of e-liquids used to refill e-cigs. SN - 2050-6511 UR - https://doi.org/10.1186/s40360-015-0030-0 DO - 10.1186/s40360-015-0030-0 ID - Panitz2015 ER -