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Table 2 Predictors of renal dysfunction after treatment with oral antiviral drugs

From: Nephrotoxicity caused by oral antiviral agents in patients with chronic hepatitis B treated in a hospital for tropical diseases in Thailand

  Univariate analysis Multivariate analysis
Patient characteristic, n = 102 Crude OR (95 % CI) P Adjusted OR (95 % CI) P
Age ≥50 years 2.63 (0.54–12.74) 0.328 1.33 (0.23–7.84) 0.752
Low body weight (<60 kg) 0.58 (0.12–2.86) 0.725 1.43 (0.25–8.35) 0.689
Nucleotides (versus nucleosides) 10.50 (2.60– 42.43) 0.001* 7.36 (1.54–35.27) 0.012*
Sex (M:F) 2.14 (0.44–10.44) 0.501 1.24 (0.20–7.56) 0.816
Diabetes mellitus 1.44 (0.28–7.43) 0.649 1.53 (0.29–7.87) 0.612
Hypertension 2.67 (0.76–9.36) 0.147 2.12 (0.55–8.17) 0.274
Cirrhosis 1.27 (0.14–11.58) 1.000 9.76 (0.71–134.0) 0.088
  1. *P <0.05
  2. OR odds ratio, CI confidence intervals, M male, F female