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Table 2 Predictors of renal dysfunction after treatment with oral antiviral drugs

From: Nephrotoxicity caused by oral antiviral agents in patients with chronic hepatitis B treated in a hospital for tropical diseases in Thailand

 

Univariate analysis

Multivariate analysis

Patient characteristic, n = 102

Crude OR (95 % CI)

P

Adjusted OR (95 % CI)

P

Age ≥50 years

2.63 (0.54–12.74)

0.328

1.33 (0.23–7.84)

0.752

Low body weight (<60 kg)

0.58 (0.12–2.86)

0.725

1.43 (0.25–8.35)

0.689

Nucleotides (versus nucleosides)

10.50 (2.60– 42.43)

0.001*

7.36 (1.54–35.27)

0.012*

Sex (M:F)

2.14 (0.44–10.44)

0.501

1.24 (0.20–7.56)

0.816

Diabetes mellitus

1.44 (0.28–7.43)

0.649

1.53 (0.29–7.87)

0.612

Hypertension

2.67 (0.76–9.36)

0.147

2.12 (0.55–8.17)

0.274

Cirrhosis

1.27 (0.14–11.58)

1.000

9.76 (0.71–134.0)

0.088

  1. *P <0.05
  2. OR odds ratio, CI confidence intervals, M male, F female