Skip to main content

Table 2 Antibiotic sensitivity and antibiotic resistance for different drug groups in patients with pneumonia caused by Serratia marcescens

From: Cefepime shows good efficacy and no antibiotic resistance in pneumonia caused by Serratia marcescens and Proteus mirabilis – an observational study

No. of patients with S. marcescens = 43

       

Drug groups

Active substance

No. using antibiotics (%)

No. of tests of antibiotics on antibiogram (%)

Sensitive (%)

Intermediate (%)

Resistant (%)

P value compared to ampicillin

Penicillins

Ampicillin

0

43 (100)

0

0

43 (100)

 
 

Piperacillin

0

43 (100)

31 (72.1)

5 (11.6)

7 (16.3)

< 0.0001

Penicillin + Beta-lactamase inhibitors

Ampicillin + Sulbactam

3 (7.0)

43 (100)

0

0

43 (100)

1.0

 

Piperacillin + Tazobactam

21 (48.8)

43 (100)

38 (88.3)

1 (2.3)

4 (9.3)

< 0.0001

Cephalosporins

Cefepime

2 (4.7)

39 (90.7)

39 (100)

0

0

< 0.0001

 

Cefotaxime

0

43 (100)

36 (83.7)

2 (4.7)

5 (11.6)

< 0.0001

 

Ceftazidime

1 (2.3)

39 (90.7)

39 (100)

0

0

< 0.0001

 

Cefuroxime

4 (9.3)

43 (100)

0

0

43 (100)

1.0

Glycylcycline

Tetracycline

0

17 (39.5)

3 (17.6)

2 (11.8)

12 (70.6)

0.001

 

Tigecycline

0

5 (11.6)

3 (60.0)

2 (40.0)

0

< 0.0001

Carbapenems

Imipenem

5 (11.6)

43 (100)

42 (97.7)

0

1 (2.3)

< 0.0001

 

Meropenem

2 (4.7)

42 (97.7)

41 (97.6)

1 (2.4)

0

< 0.0001

Gyrase inhibitors

Ciprofloxacin

4 (9.3)

42 (97.7)

37 (88.1)

2 (4.8)

3 (7.1)

< 0.0001

 

Levofloxacin

3 (7.0)

28 (65.1)

26 (92.9)

0

2 (7.1)

< 0.0001

Aminoglycoside

Amikacin

0

26 (60.5)

18 (69.2)

8 (30.8)

0

< 0.0001

 

Gentamicin

2 (4.7)

40 (93.0)

38 (95.0)

2 (5.0)

0

< 0.0001

 

Tobramycin

0

27 (62.8)

16 (59.3)

4 (14.8)

7 (25.9)

< 0.0001

Trimethoprim + Sulfamethoxazole

Co-trimoxazole

0

42 (97.7)

39 (92.9)

0

3 (7.1)

< 0.0001

Others

Fosfomycin

0

17 (39.5)

17 (100)

0

0

< 0.0001

  1. Note: Significant P values shown in bold