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Table 2 Antibiotic sensitivity and antibiotic resistance for different drug groups in patients with pneumonia caused by Serratia marcescens

From: Cefepime shows good efficacy and no antibiotic resistance in pneumonia caused by Serratia marcescens and Proteus mirabilis – an observational study

No. of patients with S. marcescens = 43        
Drug groups Active substance No. using antibiotics (%) No. of tests of antibiotics on antibiogram (%) Sensitive (%) Intermediate (%) Resistant (%) P value compared to ampicillin
Penicillins Ampicillin 0 43 (100) 0 0 43 (100)  
  Piperacillin 0 43 (100) 31 (72.1) 5 (11.6) 7 (16.3) < 0.0001
Penicillin + Beta-lactamase inhibitors Ampicillin + Sulbactam 3 (7.0) 43 (100) 0 0 43 (100) 1.0
  Piperacillin + Tazobactam 21 (48.8) 43 (100) 38 (88.3) 1 (2.3) 4 (9.3) < 0.0001
Cephalosporins Cefepime 2 (4.7) 39 (90.7) 39 (100) 0 0 < 0.0001
  Cefotaxime 0 43 (100) 36 (83.7) 2 (4.7) 5 (11.6) < 0.0001
  Ceftazidime 1 (2.3) 39 (90.7) 39 (100) 0 0 < 0.0001
  Cefuroxime 4 (9.3) 43 (100) 0 0 43 (100) 1.0
Glycylcycline Tetracycline 0 17 (39.5) 3 (17.6) 2 (11.8) 12 (70.6) 0.001
  Tigecycline 0 5 (11.6) 3 (60.0) 2 (40.0) 0 < 0.0001
Carbapenems Imipenem 5 (11.6) 43 (100) 42 (97.7) 0 1 (2.3) < 0.0001
  Meropenem 2 (4.7) 42 (97.7) 41 (97.6) 1 (2.4) 0 < 0.0001
Gyrase inhibitors Ciprofloxacin 4 (9.3) 42 (97.7) 37 (88.1) 2 (4.8) 3 (7.1) < 0.0001
  Levofloxacin 3 (7.0) 28 (65.1) 26 (92.9) 0 2 (7.1) < 0.0001
Aminoglycoside Amikacin 0 26 (60.5) 18 (69.2) 8 (30.8) 0 < 0.0001
  Gentamicin 2 (4.7) 40 (93.0) 38 (95.0) 2 (5.0) 0 < 0.0001
  Tobramycin 0 27 (62.8) 16 (59.3) 4 (14.8) 7 (25.9) < 0.0001
Trimethoprim + Sulfamethoxazole Co-trimoxazole 0 42 (97.7) 39 (92.9) 0 3 (7.1) < 0.0001
Others Fosfomycin 0 17 (39.5) 17 (100) 0 0 < 0.0001
  1. Note: Significant P values shown in bold