Table 3 Antibiotic sensitivity and antibiotic resistance in different drug groups in patients with pneumonia caused by Proteus mirabilis
No. of patients with P. mirabilis = 20 | |||||||
|---|---|---|---|---|---|---|---|
Drug groups | Active substance | No. using antibiotics (%) | No. of tests of antibiotics on antibiogram (%) | Sensitive (%) | Intermediate (%) | Resistant (%) | P value compared to ampicillin |
Penicillins | Ampicillin | 0 | 20 (100) | 8 (40.0) | 1 (5.0) | 11 (55.0) | |
Piperacillin | 1 (5.0) | 20 (100) | 13 (65.0) | 4 (20.0) | 3 (15.0) | 0.023 | |
Penicillin + Beta-lactamase inhibitors | Ampicillin + Sulbactam | 3 (15.0) | 20 (100) | 13 (65.0) | 3 (15.0) | 4 (20.0) | 0.065 |
Piperacillin + Tazobactam | 15 (75.0) | 20 (100) | 20 (100) | 0 | 0 | 0.0002 | |
Cephalosporins | Cefepime | 0 | 19 (95.0) | 19 (100) | 0 | 0 | 0.0003 |
Cefotaxime | 0 | 20 (100) | 18 (90.0) | 0 | 2 (10.0) | 0.004 | |
Ceftazidime | 1 (5.0) | 16 (80.0) | 16 (100) | 0 | 0 | 0.0007 | |
Cefuroxime | 0 | 20 (100) | 15 (75.0) | 0 | 5 (25.0) | 0.068 | |
Glycylcycline | Tetracycline | 0 | 13 (65.0) | 0 | 0 | 13 (100) | 0.018 |
Tigecycline | 0 | 1 (5.0) | 1 (100) | 0 | 0 | 0.497 | |
Carbapenems | Imipenem | 3 (15.0) | 20 (100) | 19 (95.0) | 1(5.0) | 0 | 0.0004 |
Meropenem | 0 | 19 (95.0) | 18 (94.7) | 1 (5.3) | 0 | 0.0006 | |
Gyrase inhibitors | Ciprofloxacin | 1 (5.0) | 18 (90.0) | 15 (83.3) | 1 (5.6) | 2 (13.3) | 0.016 |
Levofloxacin | 1 (5.0) | 14 (70.0) | 13 (92.9) | 1 (7.1) | 0 | 0.003 | |
Aminoglycoside | Amikacin | 0 | 9 (45.0) | 9 (100) | 0 | 0 | 0.01 |
Gentamicin | 2 (10.0) | 19 (95.0) | 16 (84.2) | 0 | 3 (15.8) | 0.080 | |
Tobramycin | 0 | 11 (55.0) | 8 (72.7) | 1 (9.1) | 2 (18.2) | 0.139 | |
Trimethoprim + Sulfamethoxazole | Co-trimoxazole | 0 | 20 (100) | 14 (70.0) | 0 | 6 (30.0) | 0.321 |
Others | Fosfomycin | 0 | 5 (25.0) | 5 (100) | 0 | 0 | 0.056 |