Protocol: changes in rates of opioid overdose and poisoning events in an integrated health system following the introduction of a formulation of OxyContin® with abuse-deterrent properties

Table 4 Sample size needed to detect various effect sizes

Reduction in rate of overdose/poisoning events	80 % power	90 % power
25 %	16,617	22,239
50 %	3635	4865
75 %	1378	1845

ISSN: 2050-6511