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Table 4 Sample size needed to detect various effect sizes

From: Protocol: changes in rates of opioid overdose and poisoning events in an integrated health system following the introduction of a formulation of OxyContin® with abuse-deterrent properties

Reduction in rate of overdose/poisoning events 80 % power 90 % power
25 % 16,617 22,239
50 % 3635 4865
75 % 1378 1845