From: Incorporating pharmacodynamic considerations into caffeine therapeutic drug monitoring in preterm neonates
Dosing regimens
Number of patients
Caffeine serum concentration (mg/L)
40/5 mg/kg
q12h
47
23 (18–26)***
20/5 mg/kg
q24h
49
15 (11–17)
8
17 (13–20)
5/5 mg/kg
6
13 (8–17)
5
22 (21–23)