| |
Non-vitamin D
|
Higher-dose Calcitriol
|
Cholecalciferol
|
P value
|
|---|
|
No. of subjects
|
69
|
16
|
16
| |
|
CD4+ T cells/μl
|
677 (373–1043)
|
458 (315–879)
|
595 (352–1070)
|
0.544
|
|
Tregs/μl*
|
3.1 (1.6–5.3)
|
2.3 (1.2–4.1)
|
4.7 (3–8.5)
|
0.021
|
|
Helios+ Tregs/μl*
|
0.7 (0.3–1.4)
|
0.4 (0.2–1.6)
|
2.2 (1.1–3.8)
|
0.001
|
|
Helios− Tregs/μl*
|
2.2 (0.9–3.9)
|
1.4 (0.9–3)
|
2.7 (1.1–4.6)
|
0.393
|
|
IFNg+ Tregs/μl*
|
0.3 (.04–0.3)
|
0.16 (0.06–0.4)
|
0.2 (0.1–0.7)
|
0.06
|
|
CTLA-4+ Tregs/μl*
|
0.4 (0.2–0.9)
|
0.25 (0–0.7)
|
1.2 (0.2–3.5)
|
0.018
|
|
Treg/CD4+ T cells %
|
0.45 (0.29–0.78)
|
0.44 (0.25–0.95)
|
0.84 (0.53–1.4)
|
0.006
|
|
Treg/ CD8+ T cells %
|
0.84 (0.37–1.5)
|
0.57 (0.27–1.2)
|
1.4 (0.9–1.8)
|
0.058
|
|
Helios+/ Helios− Tregs
|
0.38 (0.27–0.61)
|
0.28 (0.19–0.97)
|
0.65 (0.38–1.4)
|
0.048
|
- Tregs denoted with asterisks have the marker combination CD4+ CD25+ CD127− Foxp3+
