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Table 4 Pairwise comparisons of p-values of Helios+, CTLA-4, and Treg differences, in addition to Treg subset ratios among non-vitamin D, calcitriol and cholecalciferol groups based on Kruskal-Wallis test (n = 101)

From: Low-dose oral cholecalciferol is associated with higher numbers of Helios+ and total Tregs than oral calcitriol in renal allograft recipients: an observational study

  Non-vitamin D Higher-dose Calcitriol Cholecalciferol P value
No. of subjects 69 16 16  
Total Tregs*   0.349
  0.009
  0.016
Helios+ Tregs*   0.553
  0.002
  0.001
CTLA-4+ Tregs*   0.152
  0.005
  0.034
Treg/CD4+ T cells %   0.951
  0.012
  0.002
Helios+/ Helios Tregs   0.507
  0.024
  0.027
  1. P values ≤ 0.016 were considered significant due to Bonferroni correction of α-values for multiple comparisons. Significant p-values are bold printed. Asterisks refer to Tregs with the marker combination CD4+ CD25+ CD127 Foxp3+