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Table 3 Effect of MDMA administration in plasma AST, ALT, CK-MB and CK levels

From: “Ecstasy” toxicity to adolescent rats following an acute low binge dose

  Control MDMA
AST (U/L) 39.14 ± 17.53 45.71 ± 19.44
ALT (U/L) 25.00 ± 2.00 28.57 ± 3.82
CK (U/L) 202.57 ± 76.80 200.29 ± 75.54
CK-MB (U/L) 340.14 ± 138.90 305.86 ± 132.91
  1. Plasma levels of total creatine kinase (CK), creatine kinase-MB (CK-MB), aspartate aminotransferase (AST) and alanine aminotransferase (ALT) of control and MDMA-treated rats. Results of CK, CK-MB, AST and ALT plasma levels are presented as mean ± standard deviation, and were obtained from six to seven animals in each group. Statistical comparisons were made using the t-test for CK, CK-MB and AST levels, and the Mann-Whitney Rank Sum test for ALT levels