Fig. 5
From: Virtual screening and experimental validation of novel histone deacetylase inhibitors
Nuclear morphological changes and apoptotic HepG2 and MDA-MB-231 cells treated with ZINC12555961 (90 μM) and DMSO for 48 h. Arrows indicate apoptotic nuclei. a HepG2 cells by DAPI staining treated with DMSO. b HepG2 cells by DAPI staining treated with ZINC12555961. c MDA-MB-231 cells by DAPI staining treated with DMSO. d MDA-MB-231 cells by DAPI staining treated with ZINC12555961