Table 5 The EF values and functional thresholds for the top 1, 5, 10 and 20Â % of the decoy database in combined docking function test
From: Virtual screening and experimental validation of novel histone deacetylase inhibitors
Top (%) | Docking functions | EF | |||
|---|---|---|---|---|---|
ChemPLP | Chemscore | 1T64 | 1T67 | 1T69 | |
1 | 71.8 | 22.8 | 4.84 | 4.54 | 4.98 |
5 | 67.4 | 17.6 | 4.37 | 4.21 | 4.43 |
10 | 62.1 | 14.2 | 3.53 | 3.84 | 3.81 |
20 | 57.5 | 12.3 | 3.24 | 3.31 | 3.42 |