Fig. 8

Microscopic observation of mouse liver sections that had been stained with hematoxylin and eosin at × 400. Liver sections from control mice with normal cytoarchitecture. b Iron-overloaded (iron dextran, 100 mg/kg b.w.) liver section demonstrates degeneration of cellular boundaries, fatty ballooning deterioration, inflammation (I), and necrosis (N). c Desirox-treated liver sections demonstrate reduced necrotic area. d Liver section from the R2 mouse group improved histology with portal inflammation (PI). e Liver section from the R4 mouse group (f) Liver section from the R8 mouse group (g). Liver section from the S2 mouse group (h). Liver section from the S4 mouse group (i). Liver section from the S8 mouse group demonstrates improved histology with minimal necrotic area