Fig. 1
From: Placental transfer and mammary excretion of a novel angiotensin receptor blocker fimasartan in rats
Fimasartan concentrations in a plasma and b tissues in pregnant rats after i.v. injection (2.7 and 5.5 mg/kg) followed by i.v. infusion (0.17 and 0.34 mg/h/kg) for target Css, plasma of 100 (n = 6) and 200 ng/mL (n = 5), respectively. Bold (target Css, plasma = 100 ng/mL) and dashed (target Css, plasma = 200 ng/mL) lines are the 10 and 90 % prediction intervals. Data are presented as the mean ± S.D. *: p < 0.05, 100 vs. 200 ng/mL