Table 2 To represent the IC50 values in absence (control) and presence (test concentrations) of test statins
From: Current statins show calcium channel blocking activity through voltage gated channels
Statins | CCRCs specifications | IC50 Log [Ca++]M |
|---|---|---|
Simvastatin | Control | −2.54 ± 0.04 |
Test concentration 4.6 μg/ml | −1.84 ± 0.03** | |
Atorvastatin | Control | −2.48 ± 0.06 |
Test concentration 23.1 μg/ml | −1.99 ± 0.04** | |
Test concentration 30.8 μg/ml | −1.68 ± 0.03** | |
Fluvastatin | Control | −2.11 ± 0.05 |
Test concentration 9.61 μg/ml | −1.56 ± 0.03** | |
Rosuvastatin | Control | −2.44 ± 0.03 |
Test concentration 6.6 μg/ml | −2.17 ± 0.03** | |
Verapamil | Control | −2.45 ± 0.06 |
Test concentration 0.1 μM | −1.69 ± 0.05** |