Skip to main content

Table 2 To represent the IC50 values in absence (control) and presence (test concentrations) of test statins

From: Current statins show calcium channel blocking activity through voltage gated channels

Statins CCRCs specifications IC50 Log [Ca++]M
Simvastatin Control −2.54 ± 0.04
Test concentration 4.6 μg/ml −1.84 ± 0.03**
Atorvastatin Control −2.48 ± 0.06
Test concentration 23.1 μg/ml −1.99 ± 0.04**
Test concentration 30.8 μg/ml −1.68 ± 0.03**
Fluvastatin Control −2.11 ± 0.05
Test concentration 9.61 μg/ml −1.56 ± 0.03**
Rosuvastatin Control −2.44 ± 0.03
Test concentration 6.6 μg/ml −2.17 ± 0.03**
Verapamil Control −2.45 ± 0.06
Test concentration 0.1 μM −1.69 ± 0.05**
  1. ** P < 0.05; test vs respective control