Study | Number of metformin-treated patients | Prevalence | Mean age (years) | Mean metformin dose (gram) | Mean metformin duration of use (years) | Study setting | Exclusion of renally-impaired patients |
---|---|---|---|---|---|---|---|
De Jager et al. [3] | 196 | 9.9 %a | 64 | 2.1 | 4.3 | Outpatient clinics of 3 non-academic hospitals, The Netherlands | Yes |
Reinstatler et al. [4] | 575 | 5.8 % | 63.4 | NA | 5b | NHANES sample, United States | Yes |
Hermann et al. [5] | 53 | 8 % | 58.5 | 2.2 | 5.2 | Outpatient diabetes clinic of a general hospital, Sweden | Yes |
Calvo Romero and Ramiro Lozano [9] | 81 | 8.6 % | 71.6 | 1.8 | 3.6 | Internal medicine clinic of a first level hospital, Spain | No |
Beulens et al. [11] | 550 | 28.1 % | 61.6 | 1.3 | 5.3 | 4 primary care centers, The Netherlands | No |
De Groot-Kamphuis et al. [8] | 164 | 14.1 % | 62.6 | - | 4.9b | Secondary care outpatient diabetes clinic, The Netherlands | No |
This study | 121 | 28.1 % | 58.5 | 2.4 | 9.6 | Outpatient diabetes clinics of 2 tertiary hospitals, South Africa | Yes |