Fig. 5

a-c Striatal NE, DA and 5HT (mean ± sem) for each sex, percent of WT Cu0 control mean.. The MTKO males had significantly(p < 0.005) higher 5HT level than WT males. Number of rats/condition: Wildtype Cu0 males = 16, Wildtype Cu0 females = 13; Wildtype Cu10 males = 23; Wildtype Cu10 females = 13; MTKO Cu0 males = 11; MTKO Cu0 females = 19; MTKO Cu10 males = 10; MTKO Cu10 females = 15. d-e Striatal DA and 5HT turnover (mean ± sem) for each sex, percent of WT Cu0 control mean. There was a significant (p < 0.05) decrease in DA turnover caused by Cu10