BMC Pharmacology and Toxicology

Table 5 Criteria of integrated PK/PD model adequacy for each measured response

From: Pharmacokinetic and pharmacodynamic characterization of a novel formulation containing co-formulated interferons alpha-2b and gamma in healthy male volunteers

IFN	Criteria	Neopterin	β₂M	2′–5′ OAS1	Temperature
alpha-2b	AIC	1218	1099	2122	1593
alpha-2b	R²	0.959	0.943	0.969	0.834
gamma	AIC	1569	1334	2283	1721
gamma	R²	0.952	0.946	0.931	0.839

AIC Akaike Information Criterion

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ISSN: 2050-6511

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