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Table 2 Results of pulmonary function tests and symptom scores recorded at baseline (visit 1) and after 2 days (visit 2) and 7 days (visit 3) of treatment with deflazacort or prednisolone in pediatric patients with moderate asthma exacerbation. Reproduced with permission from [11]

From: Deflazacort: therapeutic index, relative potency and equivalent doses versus other corticosteroids

 

Visit 1

Visit 2

Visit 3

 

Deflazacort

Prednisolone

Deflazacort

Prednisolone

Deflazacort

Prednisolone

FEV1 (%)

53 (13.3)

51 (14.9)

75* (15.8)

78* (20.3)

86*,** (14.3)

84* (18.6)

PEFR (l/min)

169.3 (65.3)

165.4 (79.3)

233* (84.7)

214 (75.5)

285* (113.4)

253* (114.8)

Symptom scores

6.1 (1.4)

6.5 (1.4)

1.7* (1.2)

2.7* (1.2)

0.7*,** (0.8)

0.6*,** (0.8)

  1. *Significantly different (p < 0.05) versus visit 1; **Significantly different (p < 0.05) versus visit 2; FEV1: Forced Expiratory Volume in one second; PEFR: Peak Expiratory Flow Rate