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Table 3 Relative potencies and equivalent doses of corticosteroids [Modified from 20]

From: Deflazacort: therapeutic index, relative potency and equivalent doses versus other corticosteroids

 

Equivalent glucocorticoid dose (mg)

Potency relative to hydrocortisone (cortisol) (antiiflammatory activity)

Potency relative to hydrocortisone (cortisol) (mineralcorticoid activity)

Short acting

 Hydrocortisone (cortisol)

20

1

1

 Cortisone acetate

25

0.8

0.8

Intermediate acting

 Prednisone

5

4

0.8

 Prednisolone

5

4

0.8

 Triamcinolone

4

5

N/A

 Methylprednisolone

4

5

0.5

Long acting

 Dexamethasone

0.75

30

N/A

 Betamethasone

0.6

30

N/A

Mineralcorticoids

 Fludrocortisone

N/A

15

150

 Aldosterone

N/A

N/A

400

  1. The numbers in the table indicate corticosteroid potency and equivalent doses relative to cortisol (by convention, cortisol = 1), and have been calculated by the Author on the basis of currently available literature data. N/A, not applicable
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BMC Pharmacology and Toxicology

ISSN: 2050-6511

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