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Table 1 The inhibition ratio of the 130 chemicals

From: Identification and application of anti-inflammatory compounds screening system based on RAW264.7 cells stably expressing NF-κB-dependent SEAP reporter gene

Compound No.

Inhibition ratio (%)

Compound No.

Inhibition ratio (%)

Compound No.

Inhibition ratio (%)

w1

-11.65 ± 1.29

k26

-14.74 ± 2.00

z4

-44.29 ± 19.53

w2

-23.07 ± 8.68

k27

-16.02 ± 1.17

z5

-39.52 ± 17.50

w3

-9.38 ± 1.53

k28

1.64 ± 3.12

z6

-19.94 ± 3.85

w4

-2.92 ± 2.03

k30

-14.45 ± 3.33

z7

-35.50 ± 16.85

w5

-12.74 ± 2.48

k32

-13.99 ± 2.33

z8

-29.85 ± 15.10

w6

-6.40 ± 2.60

k34

6.06 ± 2.06

z9

-35.72 ± 16.32

w7

2.21 ± 3.22

k35

-9.43 ± 2.00

z10

-13.67 ± 11.87

w8

4.85 ± 5.55

k36

4.81 ± 8.98

z11

-21.48 ± 7.93

w9

6.41 ± 7.79

k37

-4.56 ± 0.75

z12

-22.78 ± 7.29

W10

27.20 ± 5.91***

k38

-6.22 ± 1.40

z13

-38.60 ± 16.45

w11

12.99 ± 0.34**

k33

-4.24 ± 3.08

z14

-42.24 ± 19.10

w12

4.49 ± 8.32

k40

-4.84 ± 0.62

z15

-9.32 ± 10.93

w13

-2.24 ± 2.98

x1

-10.09 ± 0.37

z16

-17.9 ± 13.51

w14

-2.85 ± 2.72

x2

-13.39 ± 0.83

z17

-16.95 ± 15.87

w15

42.95 ± 28.87*

x3

-6.83 ± 2.87

z18

-10.58 ± 10.06

w19

15.76 ± 5.56**

x4

-9.21 ± 3.05

z19

6.12 ± 6.76

w20

29.82 ± 10.13**

x5

-2.57 ± 1.20

z20

-13.51 ± 4.73

w21

-10.04 ± 1.59

x6

-8.41 ± 0.48

z21

-4.97 ± 4.55

w22

-12.64 ± 4.55

x8

-3.20 ± 0.43

z22

-2.92 ± 4.35

w23

-12.17 ± 3.76

x9

9.43 ± 1.85*

s1

15.23 ± 1.85**

k1

-8.45 ± 3.57

x10

-4.75 ± 0.60

s2

6.82 ± 1.28

k2

-2.86 ± 1.86

x11

-3.74 ± 0.85

s3

26.57 ± 6.43***

k3

-5.10 ± 1.92

x12

-3.49 ± 0.63

s4

10.68 ± 3.97*

k4

-11.37 ± 3.07

x13

-6.20 ± 9.91

s5

-0.58 ± 3.33

k5

-4.99 ± 1.116

x14

-14.30 ± 9.40

s6

-3.90 ± 6.65

k6

-2.10 ± 1.52

x15

-20.12 ± 16.57

s7

-11.21 ± 2.75

k7

-4.36 ± 2.82

x16

-37.86 ± 6.55

s8

-14.82 ± 6.92

k8

-2.22 ± 3.39

x17

-31.71 ± 2.97

s9

-9.54 ± 3.42

k9

-6.56 ± 2.32

x18

-41.94 ± 8.21

s10

-23.73 ± 7.42

k10

-4.30 ± 2.47

x19

-26.51 ± 20.62

s11

-14.65 ± 5.85

k11

-3.05 ± 2.17

x20

-14.09 ± 8.09

s12

-6.06 ± 25.05

k12

5.12 ± 0.42

x21

-25.66 ± 11.07

s13

-11.09 ± 2.86

k13

8.26 ± 2.57

x22

5.25 ± 18.74

s14

-4.31 ± 2.64

k14

9.31 ± 2.81

x23

4.80 ± 1.82

s15

20.42 ± 2.62***

k15

5.30 ± 1.41

x24

7.56 ± 9.16

s16

4.57 ± 5.97

k16

12.63 ± 2.95*

x25

-7.50 ± 5.60

s17

11.34 ± 1.90

k17

6.19 ± 0.75

x26

3.62 ± 5.16

s18

16.33 ± 9.43*

k18

-6.14 ± 0.96

x27

0.19 ± 3.65

s19

-5.27 ± 3.55

k20

3.80 ± 0.79

x28

11.67 ± 10.08

s20

19.63 ± 2.34***

k21

-2.91 ± 0.58

x29

-1.12 ± 8.86

s22

6.79 ± 4.18

k22

-0.02 ± 2.30

x30

-3.87 ± 3.32

s23

-6.96 ± 4.91

k23

1.35 ± 1.78

z1

-23.43 ± 13.80

s24

-16.02 ± 6.30

k24

-2.47 ± 2.41

z2

-28.88 ± 17.48

PDTC

50.35 ± 1.36

k25

-4.87 ± 1.48

z3

-19.87 ± 11.88

  
  1. The result showed as the format of “Mean ± SEM”
  2. The “*” means that the column had significant difference compared with the control, P < 0.05; **P < 0.01; and ***P < 0.001