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Table 1 The inhibition ratio of the 130 chemicals

From: Identification and application of anti-inflammatory compounds screening system based on RAW264.7 cells stably expressing NF-κB-dependent SEAP reporter gene

Compound No. Inhibition ratio (%) Compound No. Inhibition ratio (%) Compound No. Inhibition ratio (%)
w1 -11.65 ± 1.29 k26 -14.74 ± 2.00 z4 -44.29 ± 19.53
w2 -23.07 ± 8.68 k27 -16.02 ± 1.17 z5 -39.52 ± 17.50
w3 -9.38 ± 1.53 k28 1.64 ± 3.12 z6 -19.94 ± 3.85
w4 -2.92 ± 2.03 k30 -14.45 ± 3.33 z7 -35.50 ± 16.85
w5 -12.74 ± 2.48 k32 -13.99 ± 2.33 z8 -29.85 ± 15.10
w6 -6.40 ± 2.60 k34 6.06 ± 2.06 z9 -35.72 ± 16.32
w7 2.21 ± 3.22 k35 -9.43 ± 2.00 z10 -13.67 ± 11.87
w8 4.85 ± 5.55 k36 4.81 ± 8.98 z11 -21.48 ± 7.93
w9 6.41 ± 7.79 k37 -4.56 ± 0.75 z12 -22.78 ± 7.29
W10 27.20 ± 5.91*** k38 -6.22 ± 1.40 z13 -38.60 ± 16.45
w11 12.99 ± 0.34** k33 -4.24 ± 3.08 z14 -42.24 ± 19.10
w12 4.49 ± 8.32 k40 -4.84 ± 0.62 z15 -9.32 ± 10.93
w13 -2.24 ± 2.98 x1 -10.09 ± 0.37 z16 -17.9 ± 13.51
w14 -2.85 ± 2.72 x2 -13.39 ± 0.83 z17 -16.95 ± 15.87
w15 42.95 ± 28.87* x3 -6.83 ± 2.87 z18 -10.58 ± 10.06
w19 15.76 ± 5.56** x4 -9.21 ± 3.05 z19 6.12 ± 6.76
w20 29.82 ± 10.13** x5 -2.57 ± 1.20 z20 -13.51 ± 4.73
w21 -10.04 ± 1.59 x6 -8.41 ± 0.48 z21 -4.97 ± 4.55
w22 -12.64 ± 4.55 x8 -3.20 ± 0.43 z22 -2.92 ± 4.35
w23 -12.17 ± 3.76 x9 9.43 ± 1.85* s1 15.23 ± 1.85**
k1 -8.45 ± 3.57 x10 -4.75 ± 0.60 s2 6.82 ± 1.28
k2 -2.86 ± 1.86 x11 -3.74 ± 0.85 s3 26.57 ± 6.43***
k3 -5.10 ± 1.92 x12 -3.49 ± 0.63 s4 10.68 ± 3.97*
k4 -11.37 ± 3.07 x13 -6.20 ± 9.91 s5 -0.58 ± 3.33
k5 -4.99 ± 1.116 x14 -14.30 ± 9.40 s6 -3.90 ± 6.65
k6 -2.10 ± 1.52 x15 -20.12 ± 16.57 s7 -11.21 ± 2.75
k7 -4.36 ± 2.82 x16 -37.86 ± 6.55 s8 -14.82 ± 6.92
k8 -2.22 ± 3.39 x17 -31.71 ± 2.97 s9 -9.54 ± 3.42
k9 -6.56 ± 2.32 x18 -41.94 ± 8.21 s10 -23.73 ± 7.42
k10 -4.30 ± 2.47 x19 -26.51 ± 20.62 s11 -14.65 ± 5.85
k11 -3.05 ± 2.17 x20 -14.09 ± 8.09 s12 -6.06 ± 25.05
k12 5.12 ± 0.42 x21 -25.66 ± 11.07 s13 -11.09 ± 2.86
k13 8.26 ± 2.57 x22 5.25 ± 18.74 s14 -4.31 ± 2.64
k14 9.31 ± 2.81 x23 4.80 ± 1.82 s15 20.42 ± 2.62***
k15 5.30 ± 1.41 x24 7.56 ± 9.16 s16 4.57 ± 5.97
k16 12.63 ± 2.95* x25 -7.50 ± 5.60 s17 11.34 ± 1.90
k17 6.19 ± 0.75 x26 3.62 ± 5.16 s18 16.33 ± 9.43*
k18 -6.14 ± 0.96 x27 0.19 ± 3.65 s19 -5.27 ± 3.55
k20 3.80 ± 0.79 x28 11.67 ± 10.08 s20 19.63 ± 2.34***
k21 -2.91 ± 0.58 x29 -1.12 ± 8.86 s22 6.79 ± 4.18
k22 -0.02 ± 2.30 x30 -3.87 ± 3.32 s23 -6.96 ± 4.91
k23 1.35 ± 1.78 z1 -23.43 ± 13.80 s24 -16.02 ± 6.30
k24 -2.47 ± 2.41 z2 -28.88 ± 17.48 PDTC 50.35 ± 1.36
k25 -4.87 ± 1.48 z3 -19.87 ± 11.88   
  1. The result showed as the format of “Mean ± SEM”
  2. The “*” means that the column had significant difference compared with the control, P < 0.05; **P < 0.01; and ***P < 0.001