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Table 2 Recommended dose for posaconazole in renal and liver impairment patients [12]

From: A case report of intravenous posaconazole in hepatic and renal impairment patient with invasive Aspergillus terreus infection: safety and role of therapeutic drug monitoring

Population Posaconazole dose adjustment
Renal impairment  
Creatinine clearance 20-80 ml/min No adjustment necessary
Creatinine clearance < 20 ml/min No adjustment necessary, monitor for breakthrough fungal infections due to variability in exposure
Hepatic impairment  
Child-Pugh A, B, C No adjustment necessary