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Fig. 5 | BMC Pharmacology and Toxicology

Fig. 5

From: Regulation of voltage-gated potassium channels attenuates resistance of side-population cells to gefitinib in the human lung cancer cell line NCI-H460

Fig. 5

Inhibitory effect of combination treatment with gefitinib and Kv blockers (TEA and 4-AP) or an opener (flupirtine) on sorted SP cells and Non-SP cell viability. Cell viability of SP cells and Non-SP cells treated with a TEA 5 mM b 4-AP 2 mM, or c flupirtine 30 μM together gefitinib 2 μM. Results are mean ± SE of triplicate experiments, (*) p < 0.05

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