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Table 2 Viability of SP- and Non-SP cells treated with gefitinib and Kv channels blocker or Kv7 opener

From: Regulation of voltage-gated potassium channels attenuates resistance of side-population cells to gefitinib in the human lung cancer cell line NCI-H460

Cell viability (%)

Gefitinib (2 μM)

TEA (5 mM)

4-AP (2 mM)

Flupirtine (30 μM)

TEA (5 mM)

4-AP (2 mM)

Flupirtine (30 μM)

(Gef 2 μM)

Non-SP

59.68 (±4.54)

79.09 (±5.62)

72.46 (±5.45)

58.08 (±5.67)

20.39 (±3.27)

20.54 (±5.22)

32.02 (±3.48)

SP

105.32 (±10.92)

84.22 (±4.40)

83.32 (±5.43)

63.00 (±8.81)

23.84 (±4.27)

27.44 (±8.87)

30.63 (±3.95)