Fig. 8From: Long-term treatment of clarithromycin at a low concentration improves hydrogen peroxide-induced oxidant/antioxidant imbalance in human small airway epithelial cells by increasing Nrf2 mRNA expressionTime-dependent changes in extracellular (a) and intracellular (b) concentrations of CAM in SAECs. Cells were incubated with 1 μM, 5 μM or 10 μM CAM for 24, 48 or 72 h. CAM concentrations were measured using HPLC. Data are presented as means ± SD of four independent experiments. *p < 0.05, **p < 0.01 vs. cells incubated with the same concentration of CAM for 0 h. † p < 0.05, †† p < 0.01 vs. cells incubated with 10 μM CAM at each timeBack to article page