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Table 1 Reported adverse outcomes

From: Adverse drug events observed in patients with type 2 diabetes mellitus treated with 100 mg versus 300 mg canagliflozin: a systematic review and meta-analysis of published randomized controlled trials

Trials Adverse events reported Follow up (weeks)
Blonde 2016 [9] Any AEs, AEs leading to drug discontinuation, hypoglycemia episodes 104
Forst 2014 [10] Any AEs, AEs leading to discontinuation, serious AEs, deaths, UTI 52
Neal 2015 [11] Any AEs, AEs causing discontinuation, serious AEs, deaths, UTI, documented and severe hypoglycemia 18
Gonzalez 2013 [12] Any AEs, AEs leading to discontinuation, serious AEs, UTI, postural dizziness 52
Inagaki 2013 [13] Hypoglycemia 12
Inagaki 2014 Discontinuation due to AEs 52
Stenlof 2013 [15] Any AEs, AEs leading to discontinuation, serious AEs, death, UTI, postural dizziness 26
Wilding 2013 [16] Any AEs, AEs leading to discontinuation, serious AEs, deaths, UTI, hypoglycemia 52
Yale 2013 [17] Any AEs, AEs leading to discontinuation, serious AEs, deaths, UTI, postural dizziness 26
Rosenstock 2012 [18] Any AEs, serious AEs, discontinuation due to AEs, UTI, hypoglycemia 12
  1. Abbreviations: AEs adverse events, UTI urinary tract infections