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Table 1 Regimens used as the third-line treatment

From: The salvage therapy in lung adenocarcinoma initially harbored susceptible EGFR mutation and acquired resistance occurred to the first-line gefitinib and second-line cytotoxic chemotherapy

Regimen

All patients

Study cohort

Erlotinib

29 (48%)a

28 (48%)

Gefitinib

1 (2%)

 

Chemotherapy without platinum:

 Pemetrexed

1 (2%)

1 (2%)

 Gemcitabine

7 (12%)

7 (12%)

 Vinorelbine

7 (12%)

7 (12%)

 Taxanes

5 (8%)

5 (9%)

Platinum-based doublet:

 Pemetrexed + Platinum

4 (7%)

4 (7%)

 Gemcitabine + Platinum

1 (2%)

1 (2%)

 Vinorelbine + Platinum

2 (3%)

2 (3%)

 Taxanes + Platinum

3 (5%)

3 (5%)

 Total

60

58

  1. Data are presented as n (%)
  2. aIncluding one patient receiving both bevacizumab and erlotinib