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Table 3 Bivariate and multivariate analysis for level of adherence to antihypertensive drugs among hypertensive patients attending care in referral Hospitals in Northwest Ethiopia, 2016 (n = 409)

From: Drug adherence for antihypertensive medications and its determinants among adult hypertensive patients attending in chronic clinics of referral hospitals in Northwest Ethiopia

Variables Adherence status COR(95% CI) AOR(95% CI)
Adherent Non adherent
Age
 18–38 37 20 1 1
 39–59 125 68 0.99(0.54,1.84) 0.72(0.28,1.82)
  > = 60 113 46 1.33(0.70,2.53) 0.72(2.33,2.21)
Marital status
 Single 26 13 1.44(0.63,3.33) 0.78(0.23,2.62)
 Married 188 73 1.86(1.05,3.30)* 1.25(0.52, 3.04)
 divorced 25 22 0.82(0.38,1.76) 0.76(0.25,2.38)
 Widowed 36 26 1 1
Residence
 Urban 213 107 1 1
 Rural 62 27 1.15(0.69,1.92) 0.69(0.35,1.39)
Educational status
 Unable to read and write 108 42 1 1
 Able to read and write 39 18 0.84(0.43,1.63) 1.27(0.45,3.58)
 Grade 1–8 34 32 0.41(0.23,0.75)* 0.82(0.31,2.18)
 Grade 9-12 45 24 0.73(0.40,1.34) 1.52(0.52,4.46)
 Above secondary school 49 18 1.06(0.55, 2.02) 0.75(0.16,3.43)
Occupation
 Government 77 28 1 1
 Merchant 35 23 0.55(0.28,1.09) 0.99(0.39,2.55)
 Farmer 38 23 0.60(0.31,1.18) 0.33(0.09,1.17)
 House wife 70 34 0.75(0.41,1.36) 0.87(0.37,2.04)
 Others 55 26 0.77(0.41,1.45) 0.5(0.21,1.18)
Distance from the hospital(single trip)
  < =1/2 h 150 72 1.03(0.68,1.56) 0.89(0.48,1.64)
  > ½ hour 125 62 1 1
Wealth status
 Poor 81 49 1 1
 Medium 110 46 1.45(0.88,2.37) 0.92(0.44,1.92)
 Rich 84 39 1.30(0.78, 2.19) 1.05(0.36,3.08)
Setting/Hospitals/
 Gondar University 97 57 1 1
 Debre Markos 45 22 1.20(0.66,2.20) 1.28 (0.57, 2.81)
 Felege Hiwot 133 55 1.42(0.90,2.24) 1.31 (0.71,2.41)
No of co morbidities
 None 180 87 2.07(0.86,4.96) 4.36(1.34,14.12)**
 One 84 36 2.33(0.93,5.87) 3.38(1.01,11.31)**
 Two or more 11 11 1 1
B/P
 Not controlled 163 83 1 1
 Controlled 112 51 1.12(0.73,1.71) 1.07(0.55,2.06)
Duration since starting treatment
  < 3 years 99 76 1 1
  > = 3 years 176 58 2.33(1.53,3.55)* 1.89(1.1,3.35)**
Antihypertensive drugs
 One 159 72 1 1
 Two 95 53 0.81(0.53,1.26) 1.97(0.76,5.09)
 Three and above 21 9 1.06(0.46,2.42) 3.03(0.64,14.29)
Number of tabs per day:
 One 150 56 1.55(0.90,2.66) 2.09(0.97,4.53)
 Two 73 48 0.88(0.49,1.57) 1.1(0.48,2.37)
 Three and more 52 30 1 1
Dosage Frequency
 Once daily 162 63 1.62(1.07,2.45)* 1.52(0.76,3.02)
 Twice or more 113 71 1 1
Medical cost per month (birr) for hypertension
  < 50 birr 130 44 1.83(1.12,2.82)* 2.06(1.13,3.76)**
  > = 50 birr 145 90 1 1
Knowledge
 Knowledgeable 207 51 4.95(3.18,7.72)* 1.45(0.78,2.7)
 Not Knowledgeable 68 83 1 1
Attitude
 Favourable 245 42 17.89(10.57,30.28)* 9.88(5.34,18.27)**
 Unfavourable 30 92 1 1
Pt-provider relationship
 Good 224 44 8.98(5.61,14.40)* 4.27(2.32,7.86)**
 Poor 51 90 1 1
  1. * Variables those were significant during bivariate logistic analysis at P value 0.05
  2. ** Variables that was found to have significant association during multivariate analysis at p value < 0.05