Fig. 1

Dissolution profiles (percent release) of omeprazole in buffer stage with and without acid stage. a The standard sample; b one failed omeprazole sample (B-040) from Cambodia; c two failed omeprazole samples from Myanmar. Each value represents mean ± SD of three capsules except for (b) where n = 1. Significant differences were evaluated (**p < 0.01) comparing percent dissolution of the capsules in with and without acid stage at each time point using student’s t-test. For the dissolution profile of Cambodian sample only one capsule was used in each stage, the result of which was not available for statistical comparison