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Fig. 2 | BMC Pharmacology and Toxicology

Fig. 2

From: Hesperetin-5,7,3’-O-triacetate suppresses airway hyperresponsiveness in ovalbumin-sensitized and challenged mice without reversing xylazine/ketamine-induced anesthesia in normal mice

Fig. 2

Effect of orally administered HTA (10 ~ 100 μmol/kg) and roflumilast (1 and 5 mg/kg) on the airway resistance (RL) (a, c) and lung dynamic compliance (Cdyn) (b, d) in sensitized and challenged mice which received aerosolized methacholine (MCh, 6.25 ~ 25 mg/mL) 2 days after the last allergen challenge. *p < 0.05, **p < 0.01, ***p < 0.001 compared to the control (vehicle) group. # p < 0.05, ## p < 0.01, ### p < 0.001 compared to the non-challenged group. Each value represents the mean ± SEM (n = 5 ~ 12)

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BMC Pharmacology and Toxicology

ISSN: 2050-6511

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