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Table 2 Vital signs and laboratory results at baseline and after follow-up

From: Efficacy and safety of enzyme-replacement-therapy with agalsidase alfa in 36 treatment-naïve Fabry disease patients

  Baseline After follow up Frequency
Mean ± SD Mean ± SD  
Vital signs (n = 36)
 Systolic BP (mmHg) 123.0 ± 14.9 125.9 ± 14.4 every 2 weeks
 Diastolic BP (mmHg) 65.4 ± 10.9 67.8 ± 11.2 every 2 weeks
 Pulse (/min) 69.1 ± 15.3 68.7 ± 13.0 every 2 weeks
Hematological test (n = 36)
 WBC (102/mL) 59.7 ± 18.2 60.2 ± 15.0 once a month
 RBC (104/mL) 445.0 ± 34.2 446.5 ± 40.4 once a month
 Hg (g/dL) 13.2 ± 1.2 13.1 ± 1.5 once a month
 Ht (%) 39.6 ± 3.2 39.2 ± 3.7 once a month
 Plt (104/mL) 23.0 ± 6.0 23.4 ± 6.7 once a month
Blood chemistry test (n = 36)
 TP (g/dL) 7.1 ± 0.4 7.1 ± 0.4 once a month
 Alb (g/dL) 4.4 ± 0.2 4.3 ± 0.2 once a month
 T-Bil (mg/dL) 0.5 ± 0.2 0.5 ± 0.3 once a month
 ALP (U/L) 261.4 ± 155.1 239.8 ± 72.2 once a month
 AST (U/L) 22.9 ± 10.4 24.5 ± 8.2 once a month
 ALT (U/L) 18.0 ± 17.8 19.7 ± 12.0 once a month
 y-GTP (U/L) 29.9 ± 25.5 37.2 ± 29.5 once a month
 T-Cho (mg/dL) 197.3 ± 39.0 198.4 ± 37.7 once a month
 HDL (mg/dL) 72.7 ± 14.2 74.9 ± 14.2 once a month
 TG (mg/dL) 100.4 ± 65.4 108.5 ± 48.7 once a month
 LDL (mg/dL) 111.4 ± 31.6 116.0 ± 31.5 once a month
 LDH (U/L) 208.8 ± 53.0 233.0 ± 67.6 once a month
 CK (U/L) 103.4 ± 49.0 107.9 ± 50.3 once a month
 BUN (mg/dL) 12.3 ± 3.6 14.8 ± 12.3 once a month
 UA (mg/dL) 4.7 ± 1.3 4.8 ± 0.9 once a month
 Cre (mg/dL) 0.71 ± 0.13 0.92 ± 1.19 once a month
 eGFR (mL/min/1.73 m2) 83.5 ± 28.6 82.6 ± 29.4 once a month
 Na (mEq/L) 141.0 ± 2.0 140.8 ± 2.0 once a month
 Cl (mEq/L) 105.0 ± 2.3 105.7 ± 1.5 once a month
 K (mEq/L) 4.2 ± 0.3 4.4 ± 0.4 once a month
 CRP (mg/dL) 0.30 ± 1.17 0.42 ± 1.54 once a month
 hs-Trop I (pg/mL) 56.9 ± 116.8 58.0 ± 89.6 once a month
 BNP (mg/dL) 86.3 ± 149.4 62.2 ± 72.8 once a month
 β2-MG (mg/L) 1.37 ± 0.35 1.78 ± 1.98 once a month
 Cystatin C (mg/L) 0.67 ± 0.11 0.94 ± 0.90 once a month
 FT3 (pg/mL) 2.79 ± 0.38 2.94 ± 0.35 every 6 months
 FT4 (ng/dL) 1.07 ± 0.14 1.00 ± 0.15 every 6 months
 TSH (mg/dL) 1.64 ± 0.90 1.60 ± 0.82 every 6 months
Urinalysis (n = 36)
 UP/Cr ratio 0.19 ± 0.27 0.39 ± 0.72 once a month
 NAG (U/L) 4.5 ± 3.0 3.8 ± 2.4 once a month
anti-αGal Ab (n = 36) negative (n = 36) negative (n = 35) every 6 or 12 months
  positive (n = 0) positive (n = 1)