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Table 1 Non-compartmental parameters for mitiglinide after a single 10 mg oral dose in healthy volunteers (mean ± SD, n = 18)

From: Pharmacokinetic and pharmacodynamic modeling of oral mitiglinide on glucose lowering in healthy Chinese volunteers

Parameter Mean ± SD
t 1/2 (h) 1.69 ± 0.16
T max (h) 0.25 (0.17–0.50)
CL/F (L/h) 7.80 ± 1.84
Vd/F (L) 23.96 ± 7.23
C max(ng/mL) 1165.10 ± 357.50
AUC 0-t (ng/mL·h) 1489.60 ± 336.85
AUC0-∞ (ng/mL·h) 1497.20 ± 339.73
AUC0-t / AUC0-∞ (%) 99.51 ± 0. 16