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Table 1 Non-compartmental parameters for mitiglinide after a single 10 mg oral dose in healthy volunteers (mean ± SD, n = 18)

From: Pharmacokinetic and pharmacodynamic modeling of oral mitiglinide on glucose lowering in healthy Chinese volunteers

Parameter

Mean ± SD

t 1/2 (h)

1.69 ± 0.16

T max (h)

0.25 (0.17–0.50)

CL/F (L/h)

7.80 ± 1.84

Vd/F (L)

23.96 ± 7.23

C max(ng/mL)

1165.10 ± 357.50

AUC 0-t (ng/mL·h)

1489.60 ± 336.85

AUC0-∞ (ng/mL·h)

1497.20 ± 339.73

AUC0-t / AUC0-∞ (%)

99.51 ± 0. 16

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BMC Pharmacology and Toxicology

ISSN: 2050-6511

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