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Zinc as an adjunct treatment for reducing case fatality due to clinical severe infection in young infants: study protocol for a randomized controlled trial

  • Nitya Wadhwa1,
  • Sudha Basnet2,
  • Uma Chandra Mouli Natchu1,
  • Laxman P. Shrestha2,
  • Shinjini Bhatnagar1,
  • Halvor Sommerfelt10,
  • Tor A. Strand10, 11Email author,
  • the zinc sepsis study group,
  • Siddarth Ramji3,
  • K. C. Aggarwal4,
  • Harish Chellani4,
  • Anuradha Govil5,
  • Mamta Jajoo6,
  • N. B. Mathur3,
  • Meenakshi Bhatt4,
  • Anup Mohta7,
  • Imran Ansari8,
  • Srijana Basnet2,
  • Ram H. Chapagain9,
  • Ganesh P. Shah8 and
  • Binod M. Shrestha9
BMC Pharmacology and ToxicologyBMC series – open, inclusive and trusted201718:56

Received: 23 April 2017

Accepted: 26 June 2017

Published: 10 July 2017

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Open Peer Review reports

Pre-publication versions of this article and author comments to reviewers are available by contacting

Original Submission
23 Apr 2017 Submitted Original manuscript
25 May 2017 Author responded Author comments - Nitya Wadhwa
Resubmission - Version 2
25 May 2017 Submitted Manuscript version 2
26 Jun 2017 Editorially accepted
10 Jul 2017 Article published 10.1186/s40360-017-0162-5

How does Open Peer Review work?

Open peer review is a system where authors know who the reviewers are, and the reviewers know who the authors are. If the manuscript is accepted, the named reviewer reports are published alongside the article. Pre-publication versions of the article and author comments to reviewers are available by contacting All previous versions of the manuscript and all author responses to the reviewers are also available.

You can find further information about the peer review system here.

Authors’ Affiliations

Pediatric Biology Centre, Translational Health Science and Technology Institute
Department of Child Health, Institute of Medicine, Tribhuvan University
Department of Neonatology, Maulana Azad Medical College and associated Lok Nayak Hospital
Department of Pediatrics, Vardhman Mahavir Medical College & Safdarjung Hospital
Department of Pediatrics, Kasturba Hospital
Department of Pediatric Medicine, Chacha Nehru Bal Chikitsalaya
Department of Pediatric Surgery, Chacha Nehru Bal Chikitsalaya
Department of Pediatrics, Patan Academy of Health Sciences
Medical Department, Kanti Children’s Hospital
Centre for Intervention Science in Maternal and Child Health, Centre for International Health, University of Bergen
Department of Research, Innlandet Hospital Trust