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Fig. 5 | BMC Pharmacology and Toxicology

Fig. 5

From: The inhibitory effect of Isoliquiritigenin on the proliferation of human arterial smooth muscle cell

Fig. 5

H2O2 abolished effect of Isoliquiritigenin on HASMCs proliferation. After incubation with or without ISL (10 μM) in the absence or presence of H2O2 (100 μM) for 48 h, a HASMCs viability was examined by cck-8 assay. b Western blot analysis of cell extracts for detection expressions of PI3K, p-PI3K, AKT, p-AKT. Phosphorylated protein levels were calculated as a ratio relative to total protein and expressed relative to untreated HASMCs. All values represented as mean ± SD, n = 5, *: P < 0.05; **: P < 0.01 compared with untreated HASMCs. #: P < 0.05; ###: P < 0.05 compared with 100 μM H2O2 treated HASMCs. &: P < 0.05 compared with ISL treated HASMCs

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