Fig. 5From: The inhibitory effect of Isoliquiritigenin on the proliferation of human arterial smooth muscle cellH2O2 abolished effect of Isoliquiritigenin on HASMCs proliferation. After incubation with or without ISL (10 μM) in the absence or presence of H2O2 (100 μM) for 48 h, a HASMCs viability was examined by cck-8 assay. b Western blot analysis of cell extracts for detection expressions of PI3K, p-PI3K, AKT, p-AKT. Phosphorylated protein levels were calculated as a ratio relative to total protein and expressed relative to untreated HASMCs. All values represented as mean ± SD, n = 5, *: P < 0.05; **: P < 0.01 compared with untreated HASMCs. #: P < 0.05; ###: P < 0.05 compared with 100 μM H2O2 treated HASMCs. &: P < 0.05 compared with ISL treated HASMCsBack to article page