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Fig. 2 | BMC Pharmacology and Toxicology

Fig. 2

From: β adrenergic receptor/cAMP/PKA signaling contributes to the intracellular Ca2+ release by tentacle extract from the jellyfish Cyanea capillata

Fig. 2

Effect of β blockers on TE-induced Ca2+ increase in isolated adult mouse cardiomyocytes. β-blockers propranolol, atenolol and esmolol were preincubated for 5 min with the cardiomyocytes followed by 60 μg/ml TE administration with or without 1.8 mM extracellular Ca2+. a. The representative fluorescent Ca2+ scanning images of cardiomyocytes affected by the β blockers on TE-induced intracellular Ca2+ overload under 1.8 mM Ca2+ extracellular solution and Ca2+-free condition. b The traces of F/F0 values affected by the β blockers on TE-induced intracellular Ca2+ overload under 1.8 mM extracellular Ca2+ condition (n = 6). c The traces of F/F0 values affected by the β blockers on TE-induced intracellular Ca2+ overload under extracellular Ca2+ free condition. Data are shown by mean ± SD (n = 6)

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