Fig. 1
From: Short-term treatment with taurolidine is associated with liver injury
Cell survival of HepaRG cells with taurolidine treatment for 24 h was assessed by WST assay. Cell survival of seeded and adherent HepaRG cells was significantly decreased after treatment with taurolidine concentration of 500 μg/ml (a). HepaRG cells without previous adherence showed cell death at a concentration of 100 μg/ml (b). Liver enzymes in supernatants of cell cultures were analyzed and showed a significant elevation of ASAT and GLDH with increasing taurolidine concentrations (c, d). Representative data of three independent experiments are shown