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Fig. 6 | BMC Pharmacology and Toxicology

Fig. 6

From: Rosiglitazone increases endothelial cell migration and vascular permeability through Akt phosphorylation

Fig. 6

Rosiglitazone suppressed the expression of tight junction proteins. a HUVECs were treated with rosiglitazone (10 μM) with or without PI3K inhibitors LY294002 (1 μM), Akt inhibitor (3.5 μM), or PKCβ inhibitor (1.5 μM) simultaneously. Cells were stained with JAM-A antibody. b Cells were stained with ZO-1 antibody. c and d Immunoblot analysis for the expression of JAM-A and ZO-1 (n = 4)

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