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Table 1 Light microscopic pathology analysis of femur

From: Haloperidol affects bones while clozapine alters metabolic parameters - sex specific effects in rats perinatally treated with phencyclidine

  NaCl PCP NaCl-H PCP-H NaCl-C PCP-C
Trabecular area (μm2) M 25,825 ± 837 14,916 ± 689*** 16,754 ± 1590** 5875 ± 1897***## 35,615 ± 2661*** 35,624 ± 2755***###
F 34,734 ± 1073 17,380 ± 714*** 35,802 ± 2171 25,140 ± 1441***## 35,292 ± 1018 37,212 ± 977***###
  1. Effects of perinatal phencyclidine (PCP) treatment, haloperidol (H) and clozapine (C) on trabecular area of the femoral metaphysis on PN 100 in male (M) and female (F) rats. Results are presented as mean values with standard error of the mean (SEM)
  2. ** p < 0.01;*** p < 0.001 - comparing to control group
  3. ## p < 0.01; ### p < 0.001– comparing to PCP group