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Table 1 Prescription of PIMs among people with ID and from the general population

From: Prescription of potentially inappropriate medications among older people with intellectual disability: a register study

  

Yearly % with prescription

Number of years with prescription [n (%)]

Median (range)

1

2

3

4

5

6

7

All

Women

Men

At least one

gPop

27–28

1822 (35)

1093 (21)

678 (13)

501 (9)

366 (7)

352 (7)

465 (9)

n = 5277

2 (1–4)

n = 2477

2 (1–4)

n = 2800

2 (1–4)

ID

50–52

997 (17)

565 (10)

359 (6)

310 (5)

268 (5)

371 (6)

2921 (50)

n = 5791

7 (2–7)

n = 2635

6 (2–7)

n = 3156

7 (2–7)

ID vs gPop

 

<0.001

 

<0.001

 

<0.001

Anticholinergics

gPop

4–6

639 (51)

218 (18)

110 (9)

82 (7)

77 (6)

57 (5)

61 (5)

n = 1244

1 (1–3)

n = 482

1 (1–2)

n = 762

2 (1–3)

ID

9–12

545 (33)

216 (13)

180 (11)

127 (8)

106 (6)

124 (7)

372 (22)

n = 1670

3 (1–6)

n = 655

3 (1–6)

n = 1015

3 (1–6)

ID vs gPop

 

<0.001

 

<0.001

 

<0.001

Benzodiazepines

gPop

2–3

200 (47)

58 (14)

26 (6)

18 (4)

25 (6)

33 (8)

63 (15)

n = 423

2 (1–5)

n = 244

2 (1–5)

n = 179

2 (1–5)

ID

9–11

548 (34)

252 (16)

132 (8)

106 (7)

75 (5)

84 (5)

412 (26)

n = 1609

3 (1–7)

n = 722

2 (1–6)

n = 887

3 (1–7)

ID vs gPop

 

<0.001

 

0.006

 

<0.001

NSAIDsa

gPop

16–19

1961 (45)

969 (22)

582 (13)

361 (8)

228 (5)

164 (4)

107 (2)

n = 4372

2 (1–3)

n = 2092

2 (1–3)

n = 2280

2 (1–3)

ID

9–10

1422 (54)

519 (20)

259 (10)

180 (7)

87 (3)

81 (3)

80 (3)

n = 2628

1 (1–3)

n = 1331

1 (1–3)

n = 1297

1 (1–2)

ID vs gPop

 

<0.001

 

<0.001

 

<0.001

Propiomazine

gPop

2–3

369 (54)

104 (15)

58 (9)

28 (4)

38 (6)

36 (5)

46 (7)

n = 679

1 (1–3)

n = 361

1 (1–3)

n = 318

1 (1–3)

ID

7–9

344 (29)

159 (14)

101 (9)

93 (8)

85 (7)

87 (7)

306 (26)

n = 1175

3 (1–7)

n = 536

3 (1–7)

n = 639

3 (1–7)

ID vs gPop

 

<0.001

 

<0.001

 

<0.001

Tramadol

gPop

4–5

973 (65)

245 (16)

94 (6)

50 (3)

46 (3)

41 (3)

40 (3)

n = 1489

1 (1–2)

n = 747

1 (1–2)

n = 742

1 (1–2)

ID

3–3

585 (63)

150 (16)

62 (7)

42 (5)

38 (4)

17 (2)

33 (4)

n = 927

1 (1–2)

n = 488

1 (1–2)

n = 439

1 (1–2)

ID vs gPop

 

0.187

 

0.286

 

0.476

Antipsychotics (excluding lithium)

gPop

1–1

88 (37)

43 (18)

21 (9)

8 (3)

16 (7)

13 (6)

46 (20)

n = 235

2 (1–6)

n = 116

2 (1–5)

n = 119

2 (1–6)

ID

34–34

217 (7)

140 (4)

94 (3)

93 (3)

108 (3)

194 (6)

2270 (73)

n = 3116

7 (6–7)

n = 1337

7 (6–7)

n = 1779

7 (6–7)

ID vs gPop

 

<0.001

 

<0.001

 

<0.001

  1. Number of years with prescription of potentially inappropriate medications (PIMs) among 7936 people with intellectual disability (ID) and a sample from the general population (gPop) one-to-one matched on sex and age
  2. aNon-steroidal anti-inflammatory drugs
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BMC Pharmacology and Toxicology

ISSN: 2050-6511

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