Table 1 Results of the linear regression analysis of daptomycin concentrations and PT-INR
Reagent | Plasma group | R2 | β | SE (β) | P-value |
|---|---|---|---|---|---|
1: HemosIL RecombiPlasTin 2G | A (INR 1) | 0.74 | 2.2 × 10−4 | 3.3 × 10−5 | < 0.0001 |
B (warfarin, INR 2) | 0.97 | 1.5 × 10−3 | 6.0 × 10−5 | < 0.0001 | |
C (warfarin, INR 3) | 0.94 | 2.5 × 10−3 | 1.5 × 10−4 | < 0.0001 | |
D (LC, INR 2) | 0.96 | 1.3 × 10−3 | 6.5 × 10−5 | < 0.0001 | |
2: Neoplastin Plus | A (INR 1) | 0.76 | 5.1 × 10−4 | 7.3 × 10−5 | < 0.0001 |
B (warfarin, INR 2) | 0.75 | 8.6 × 10−4 | 1.2 × 10−4 | < 0.0001 | |
C (warfarin, INR 3) | 0.94 | 1.9 × 10−3 | 1.3 × 10−4 | < 0.0001 | |
D (LC, INR 2) | 0.89 | 1.4 × 10−3 | 1.2 × 10−4 | < 0.0001 | |
3: STA Neoplastin R | A (INR 1) | 0.88 | 6.6 × 10−4 | 6.0 × 10−5 | < 0.0001 |
B (warfarin, INR 2) | 0.95 | 2.4 × 10−3 | 1.3 × 10−4 | < 0.0001 | |
C (warfarin, INR 3) | 0.97 | 3.3 × 10−3 | 1.6 × 10−4 | < 0.0001 | |
D (LC, INR 2) | 0.99 | 2.2 × 10−3 | 4.7 × 10−5 | < 0.0001 |