Enoxaparin attenuates doxorubicin induced cardiotoxicity in rats via interfering with oxidative stress, inflammation and apoptosis

Table 2 Correlation between cardiotoxicity, oxidative stress, inflammation and apoptosis markers against cardiomyopathy (CMY) severity scores in male Wistar albino rats (n = 19)

Parameter	cTnI	BNP	MDA	TAC	TNF-α	IL-1β	Casp-3
Pearson r	0.627	0.591	0.635	−0.575	0.690	0.579	0.748
R square	0.393	0.349	0.404	0.330	0.477	0.335	0.560
P value	0.0040	0.008	0.004	0.010	0.001	0.009	0.0002

cTnI cardiac troponin I, BNP brain natriuretic peptide (BNP), MDA cardiac tissue malondialdehyde, TAC cardiac tissue total antioxidant capacity, TNF-α cardiac tissue tumor necrosis factor alpha; (TNF-α), IL-1β cardiac tissue interleukin 1-beta; and casp-3, cardiac tissue caspase-3. Pearson r is Pearson correlation coefficient. Positive correlation indicate parallel relationship and negative correlation indicates inverse relationship

ISSN: 2050-6511