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Table 2 Correlation between cardiotoxicity, oxidative stress, inflammation and apoptosis markers against cardiomyopathy (CMY) severity scores in male Wistar albino rats (n = 19)

From: Enoxaparin attenuates doxorubicin induced cardiotoxicity in rats via interfering with oxidative stress, inflammation and apoptosis

Parameter cTnI BNP MDA TAC TNF-α IL-1β Casp-3
Pearson r 0.627 0.591 0.635 −0.575 0.690 0.579 0.748
R square 0.393 0.349 0.404 0.330 0.477 0.335 0.560
P value 0.0040 0.008 0.004 0.010 0.001 0.009 0.0002
  1. cTnI cardiac troponin I, BNP brain natriuretic peptide (BNP), MDA cardiac tissue malondialdehyde, TAC cardiac tissue total antioxidant capacity, TNF-α cardiac tissue tumor necrosis factor alpha; (TNF-α), IL-1β cardiac tissue interleukin 1-beta; and casp-3, cardiac tissue caspase-3. Pearson r is Pearson correlation coefficient. Positive correlation indicate parallel relationship and negative correlation indicates inverse relationship