From: Improved drug safety through intensive pharmacovigilance in hospitalized pediatric patients
Variable | Without ADRs n = 1065 [mean(±SD)] | With ADRs n = 18 [mean(±SD)] | P value |
---|---|---|---|
Age (years) | 4.3 (±0.52) | 7.2 (±5.9) | NS |
Hospital stay (days) | 9 (+14) | 14 (+17) | 0.008 |
Concomitant medications | 2.3 (±1.95) | 3.7(±2.7) | 0.001 |
Number of prescribed AB | 0.78 (±0.03) | 1.3 (±0.40) | 0.001 |
Relationship with day of AB administration and ADR risk: | |||
1 day | NS | ||
2 days | NS | ||
3 days | 0.010 | ||
4 days | NS | ||
5 days | NS | ||
6 days | NS |