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Fig. 1 | BMC Pharmacology and Toxicology

Fig. 1

From: A mechanism-based pharmacokinetic model of fenofibrate for explaining increased drug absorption after food consumption

Fig. 1

Scheme showing the mechanism-based pharmacokinetic model for explaining increased fenofibrate absorption after food consumption. (Vstomach and Vduodenum: Volume of distribution in the stomach and duodenum, k g (k g ’) and k out : Gastric emptying rate constant and the elimination rate constant for calories, k m&a : Metabolism and absorption rate constant of fenofibrate, k el : Elimination rate constant, Vc/F: Volume of distribution, Efood, Ebile, EVc1 and EVc2: Parameters for explaining the effects of food on fenofibrate absorption)

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BMC Pharmacology and Toxicology

ISSN: 2050-6511

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